0216 Controlling healthy worker survivor bias of the radon-lung cancer dose-response in a cohort of uranium miners

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Healthy worker survivor bias in the Colorado Plateau uranium miners cohort.

Cohort mortality studies of underground miners have been used to estimate the number of lung cancer deaths attributable to radon exposure. However, previous studies of the radon-lung cancer association among underground miners may have been subject to healthy worker survivor bias, a type of time-varying confounding by employment status. We examined radon-mortality associations in a study of 4,1...

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Clinical measures, smoking, radon exposure, and risk of lung cancer in uranium miners.

OBJECTIVES Exposure to the radioactive daughters of radon is associated with increased risk of lung cancer in mining populations. An investigation of incidence of lung cancer following a clinical survey of Ontario uranium miners was undertaken to explore whether risk associated with radon is modified by factors including smoking, radiographic silicosis, clinical symptoms, the results of lung fu...

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Controlling the healthy worker survivor effect: an example of arsenic exposure and respiratory cancer.

OBJECTIVE This investigation sought to examine whether methods proposed to control the healthy worker survivor effect would influence the shape or magnitude of the dose-response curve for respiratory cancer induced by arsenic. METHODS Results from an unadjusted analysis are compared with results obtained by applying four different methods for control of the healthy worker survivor effect to d...

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Lung cancer among Navajo uranium miners.

Lung cancer has been a rare disease among the Indians of the southwestern United States. However, the advent of uranium mining in the area has been associated with an increased incidence of lung cancer among Navajo uranium miners. This study centers on Navajo men with lung cancer who were admitted to the hospital from February 1965 to May 1979. Of a total of 17 patients with lung cancer, 16 wer...

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Demonstration of the healthy worker survivor effect in a cohort of workers in the construction industry.

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ژورنال

عنوان ژورنال: Occupational and Environmental Medicine

سال: 2014

ISSN: 1351-0711,1470-7926

DOI: 10.1136/oemed-2014-102362.89